沃吉基因泛素化PCR Array助力PDZRN3/Cx43

在三氯乙烯过敏综合征的调控研究发表在TOP期刊

Granulysin-mediated reduction of PDZRN3 induces Cx43 gap junctions activity

exacerbating skin damage in trichloroethylene hypersensitivity syndrome

作者单位：中国疾病预防控制中心国家职业健康与毒物控制研究所

产品名称：泛素化途径PCR阵列 / Ubiquitination Pathway PCR array

产品货号：WC-MRNA0159-H

原文部分表述：

Gene expression was analyzed using a Ubiquitination Pathway PCR Array plate

(Wcgene Biotech,Shanghai,China)following the manufacturer’s instructions.

PCR Array analysis of apoptosis genes after exposure to GNLY(a) or GNLY(+) SNF(TCE) (b) in HaCaT cells,

showing mean-log10 adjusted P values. Downregulated genes with significantly different P values are shown in green, non-significantly regulated genes in gray, and upregulated genes with significantly different P values in red. 

PCR Array analysis was per-formed for three independent experiments per condition.

文章来源：

Jiao B, Zhang H, Jiang H, Liu S, Wang Y, Chen Y, Duan H, Niu Y, Shen M, Wang H, Dai Y. Granulysin-mediated reduction of PDZRN3 induces Cx43 gap junctions activity exacer-bating skin damage in trichloroethylene hypersensitivity syndrome.Ecotoxicol Environ Saf. 2024 Apr 1;274:116174. doi: 10.1016/j.ecoenv.2024.116174. Epub 2024 Mar 11. PMID: 38471344.