介绍：

         microRNA是一类由内源基因编码的长度约为22 个核苷酸的非编码单链RNA分子,在miRNA5’端2-8个碱基被称为miRNA种子序列，通过种子序列与靶 mRNA 的 5'-UTR或者3'-UTR区结合，然后利用诱导沉默复合物降解或抑制靶基因的表达。一个基因存在多个microRNA分子结合位点，在不同的研究体系中，要找到具体调控特定靶基因变化的microRNA,过去是很不容易的。沃吉基因开发出ScanMir miRNA PCR Array技术，能够快速预测出与特定靶基因结合的microRNA.

 

示意图：

基因列表

KLF4

1

2

3

4

5

6

7

8

9

10

11

12

A

hsa-let-7b

hsa-mir-1197

hsa-mir-1252

hsa-mir-1278

hsa-mir-1294

hsa-mir-1303

hsa-mir-134

hsa-mir-143

hsa-mir-145

hsa-mir-150

hsa-mir-15a

hsa-mir-182

B

hsa-mir-183

hsa-mir-186

hsa-mir-1910

hsa-mir-1914

hsa-mir-200a

hsa-mir-200b

hsa-mir-200c

hsa-mir-203

hsa-mir-206

hsa-mir-21

hsa-mir-2278

hsa-mir-2467

C

hsa-mir-299

hsa-mir-3064

hsa-mir-31

hsa-mir-3134

hsa-mir-3140

hsa-mir-3157

hsa-mir-3159

hsa-mir-3196

hsa-mir-323a

hsa-mir-329-1

hsa-mir-330

hsa-mir-335

D

hsa-mir-3529

hsa-mir-3614

hsa-mir-3619

hsa-mir-378h

hsa-mir-379

hsa-mir-380

hsa-mir-3922

hsa-mir-411

hsa-mir-4256

hsa-mir-4276

hsa-mir-429

hsa-mir-4440

E

hsa-mir-4441

hsa-mir-4453

hsa-mir-4477a

hsa-mir-4485

hsa-mir-4503

hsa-mir-4645

hsa-mir-4648

hsa-mir-4666a

hsa-mir-4756

hsa-mir-4757

hsa-mir-4763

hsa-mir-4774

F

hsa-mir-4784

hsa-mir-5047

hsa-mir-5187

hsa-mir-5191

hsa-mir-544

hsa-mir-548ar

hsa-mir-5587

hsa-mir-567

hsa-mir-5695

hsa-mir-5700

hsa-mir-5705

hsa-mir-584

G

hsa-mir-588

hsa-mir-6076

hsa-mir-612

hsa-mir-6124

hsa-mir-647

hsa-mir-648

hsa-mir-6510

hsa-mir-6529

hsa-mir-6719

hsa-mir-6773

hsa-mir-6797

hsa-mir-6816

H

hsa-mir-6831

hsa-mir-711

hsa-mir-758

hsa-mir-92b

hsa-mir-96

U6

SNORD47

SNORD68

SNORD95

NTC

NTC

NTC