Percutaneous Delivery of Hederacoside C-Loaded Nanoliposome Gel Alleviates Psoriasiform Skin
Inflammation through the CCL17/Treg Axis
含常春藤皂苷C的纳米脂质体凝胶经皮给药通过CCL17/调节性T细胞(Treg)轴减轻银屑病样皮肤炎症
原文方法介绍：
...qPCR arrays were designed to analyze a panel of inflammatory-related genes for mouse skin samples in 96-well plates according to the instructions of the manufacturer(WC-MRNA0266-M,Wcgene Biotech-nology Corporation, China)....
本研究用PCR Array全面且高效地检测与银屑病样皮肤炎症相关的多个基因表达情况，
重点聚焦于CCL17/Treg轴相关基因以及其他参与炎症反应、免疫调节等过程的基因，以此来探究疾病发生发展的分子机制，并剖析含常春藤皂苷C的纳米脂质体凝胶经皮给药后的药物作用机制。
文章来源：
Chen Y, Liang CL, Liu H, Chen H, He Y, Lin J, He Z, Qiu F, Yang B, Lu C, Dai Z. Percutaneous Delivery of Hederacoside C-Loaded Nanoliposome Gel Alleviates Psoriasiform Skin Inflammation through the CCL17/Treg Axis. ACS Appl Mater Interfaces. 2024 Sep 18;16(37):48969-48981. doi: 10.1021/acsami.4c06720. Epub 2024 Sep 5. PMID: 39233638.
